Patient's question:
Main symptoms: Congenital leg deformity. Among her four brothers, one also has a similar symptom, while the others do not. Will the descendants born to her daughter after marriage also exhibit this symptom? Onset time: All year round. Laboratory test results: No tests were conducted.Doctor's answer:
As long as one of the parents in the third generation does not carry a gene for congenital disability, it will not be passed on to the third generation. Advice: When it comes to hereditary diseases, many people have some vague concepts, thinking that hereditary diseases are just diseases that are passed down from generation to generation, or that they are terrible "incurable diseases." In fact, many hereditary diseases (especially molecular metabolic diseases), as long as they can be diagnosed early, not only can be prevented but also treated. Broadly speaking, gene therapy also includes some treatment measures taken at the DNA level. Even if the disease cannot be completely cured, it can still achieve the effect of alleviating or improving symptoms (such as using hydroxyurea and 5-azacytidine to treat sickle cell anemia and β-thalassemia). In short, it refers to a medical treatment method that changes the genetic material of human cells, which is the application of genetic principles and genetic engineering technology to treat human hereditary diseases. This type of treatment is the most ideal and has opened up broad prospects for controlling the occurrence of human hereditary diseases. Life care: Therefore, in my opinion, as long as one of the parents does not carry a pathogenic gene, the chance of the next generation getting sick is very small. Additionally, modern gene therapy methods have also become more mature.