Patient's question:
How to treat pediatric purpura nephritisDoctor's answer:
Hematuria nephritis can be classified into five types based on clinical manifestations and pathological changes: simple hematuria, acute nephritis syndrome, nephrotic syndrome, rapidly progressive nephritis, and chronic nephritis. Generally, laboratory tests combined with clinical symptoms, and even renal biopsy, are required to confirm the diagnosis. Since the severity of the disease and prognosis vary depending on the type of pathological changes, a renal biopsy may be necessary to determine the pathological classification and then formulate a comprehensive and scientific treatment plan. This disease is self-limiting, and the prognosis is generally related to the age of onset, clinical type, and pathological changes. Children under 5 years old generally recover faster than older children. The prognosis for simple hematuria is better than other types, and it can usually heal on its own within weeks to months. Next is chronic nephritis syndrome, which is often cured within 1-2 years. Patients with nephrotic syndrome often have a prolonged course, while the prognosis for rapidly progressive nephritis and chronic nephritis is poorer. The main treatments for this disease include identifying and avoiding allergens, using antibiotics for concurrent infections, and, in severe cases, using hormones, immunosuppressants, Tripterygium wilfordii, and anticoagulants. This disease is an autoimmune condition, so identifying allergens is crucial. If the allergen can be identified and exposure to it is minimized, it can help prevent recurrence.