A colleague's child has nephrotic syndrome and is experiencing lower limb edema.

Patient's question:

A colleague's child has been diagnosed with nephrotic syndrome and is experiencing lower limb edema. What should be done? Which hospital in Beijing is the most authoritative for treating children with nephrotic syndrome? Please provide an answer from a doctor.

Doctor's answer:

Nephrotic syndrome (ephrotic syndrome, NS) refers to a group of clinical symptoms, including massive proteinuria, hypoproteinemia, hyperlipidemia, and edema. Clinical characteristics: "Three highs and one low," which means massive proteinuria (≥3.5g/d), edema, hyperlipidemia, and low plasma protein (≤30g/L). Severe cases may develop pleural effusion and anuria. Suggestions: It is recommended to consult locally.
Mainly treated with immunosuppressants, general treatment, symptomatic treatment, and Chinese medicine treatment as supplementary. For patients with general treatment, bed rest is recommended; normal amounts of high-quality protein diet (1g/kg/d) and high calorie (30-50Kcal/Kg.d) are recommended. In cases of significant edema, a low-salt diet should be given; animal fat and high-cholesterol foods, such as egg yolks, should be consumed in moderation.

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