Patient's question:
What is stage 3 LGA nephropathy? Is it serious? What is the highest stage?Doctor's answer:
IgA nephropathy is a group of chronic glomerular diseases with the same immunopathological characteristics caused by multiple etiologies. In 1982, the WHO officially classified the renal pathological changes of IgA nephropathy into five grades: Grade I: Mild damage; Grade II: Minimal change with a small amount of segmental mesangial proliferation; Grade III: Focal segmental glomerulonephritis, with less than 50% of the glomeruli showing significant changes; Grade IV: Diffuse mesangial damage with proliferation and sclerosis; Grade V: Diffuse sclerosing glomerulonephritis, affecting more than 80% of the glomeruli.