Patient's question:
After a 49-day miscarriage, other tests were normal, but there was a balanced translocation on chromosomes 3 and 16.Doctor's answer:
Balanced Chromosomal Translocation: Human cells contain 23 pairs (46 chromosomes). The number and structure of chromosomes are relatively constant and cannot be arbitrarily increased or decreased, otherwise changes will occur. For example, Down syndrome is caused by having an extra copy of chromosome 21 compared to normal individuals. This can potentially reduce fertility in offspring.Patients with balanced chromosomal translocation have a high rate of miscarriage during pregnancy, or conversely, a very low pregnancy rate. The solution to this problem is to undergo third-party IVF, specifically using PGD technology, which can screen embryos for chromosomal abnormalities and select healthy embryos for transfer.