Is Down syndrome genetic?

Patient's question:

Discovery time; May 25th; No symptoms, Maternal and Child Health Hospital

Doctor's answer:

Down syndrome is caused by a chromosomal abnormality. Modern medicine has confirmed that the incidence of Down syndrome is related to the mother's age of pregnancy, involving abnormalities in chromosome 21, with three types: trisomy, translocation, and mosaicism. Advanced maternal age and aging of the egg are important reasons for nondisjunction.