Patient's question:
The death time of neonatal leukemia is generally how long! What complications usually cause deathDoctor's answer:
Congenital leukemia refers to cases that develop in newborns within the first 4 weeks of life. The vast majority are acute myeloid leukemia. Its clinical manifestations, in addition to the common features of acute leukemia, are most prominent in skin damage, which can even be the initial symptom. The skin damage is often nodular and infiltrative, with hard, movable nodules, and the surface skin is frequently blue or gray. The diameter is approximately 0.2-0.3 cm, commonly occurring on the head, face, ears, nose, or trunk, and occasionally forming ulcers. Skin damage may also manifest as papules, polymorphic erythema, hemorrhagic spots, eczema, or herpes-like lesions. Anemia is often not apparent at birth, but hemoglobin levels typically decline rapidly after birth, leading to anemia. Thrombocytopenia. White blood cell counts are generally elevated, sometimes as high as 1000 x 10^9. In acute myeloid leukemia, the percentage of myeloblasts is approximately 10% to 80%. The bone marrow findings are similar to those of leukemia at other stages. This condition can be associated with other congenital anomalies. When diagnosing this disease, it should be differentiated from neonatal sepsis, neonatal hemolytic disease, and other diseases that cause leukemoid reactions. The course of this disease is generally short, with most patients dying within 2-3 months, and it is insensitive to chemotherapy drugs.