A 1.5-year-old baby with rickets

Patient's question:

The baby is 1.5 years old. At 6 and a half months, it was found that the ribs were flaring out. When I went to the hospital for marriage, the doctor said it was because the waistband was too tight. Later, I went to another hospital for a trace element test and found mild calcium deficiency. Since then, I have been taking Diqiao. The baby started walking at 10 months. At one year old, a check-up at the hospital revealed O-shaped legs. Now the rib flaring is also very severe. The baby is taking Icicle and Diqiao, but when tested for bone density at the hospital, the doctor said there is no need to supplement calcium if there is no calcium deficiency. Please advise on how to treat this, urgently, urgently, urgently??

Doctor's answer:

Rickets, also known as vitamin D deficiency rickets, is a systemic, chronic, nutritional disease characterized by skeletal abnormalities, caused by insufficient vitamin D in infants, children, and adolescents, leading to disturbances in calcium and phosphorus metabolism. The main features include incomplete calcification of the growth plate cartilage and bone tissue in the metaphyseal ends of long bones, as well as incomplete calcification of mature bone due to vitamin D deficiency.
Guidelines: The goal is to control the active phase and prevent skeletal deformities. Treatment should primarily focus on oral administration, with a general dosage of 2,000 IU to 4,000 IU per day, or 0.5 μg to 2.0 μg of 1,25-OH2-D3, followed by a maintenance dose of 400 IU per day after one month. High-dose treatment should be reserved for strict indications. In cases of severe rickets with complications or those unable to take oral medication, a single intramuscular injection of 200,000 IU to 300,000 IU of vitamin D can be administered, followed by a maintenance dose after three months. A follow-up evaluation should be conducted one month after treatment. If there are no signs of improvement in clinical symptoms, blood biochemistry, or skeletal X-ray changes, differentiation from vitamin D-resistant rickets should be considered.
2. The Chinese Nutrition Society recommends the following daily dietary calcium intake for China: 300 mg for infants aged 0–6 months, 400 mg for infants aged 7–12 months, and 600 mg for children aged 1–3 years.

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