Pharmacology of new drugs

Author: Chen Xiaoguang
Publisher:
Publish Date: 2004-01-01
Features: This book starts with the concept, characteristics, discovery pathways, and factors influencing new drug discovery, combining chemical issues in new drugs such as the establishment of lead compounds and the formation of candidate drugs, as well as the establishment of methods and models in new drug screening. It focuses on key discussions. Additionally, it systematically introduces the basic technical requirements for pharmacological studies, the selection and evaluation of pharmacological models, the interrelationships between drug actions, the in vivo processes of drugs, and the relationship between pharmacokinetics and new drug development. On this basis, it provides a detailed introduction to some general content in new drug research, such as general pharmacology and toxicology, including genotoxicity, carcinogenicity, reproductive toxicity, systemic toxicity, and special toxicity. It pays particular attention to the intellectual property issues involved in new drug research, analyzing and comprehensively introducing them in conjunction with China's current drug management regulations. The goal is to enable medical graduate students to grasp the general process of new drug development from compound discovery to preclinical development, as well as the relevant knowledge involved. This book is primarily aimed at graduate students and researchers engaged in new drug development in medical institutions. It can serve as both a textbook and a professional reference.