Ask the expert: What is Hemoglobin A1c?

Patient's question:

Please consult the expert: What is Hemoglobin A1c? What is its relationship with diabetes?

Doctor's answer:

Hello:
Hemoglobin A1c (HbA1c) refers to the portion of hemoglobin in the blood that has combined with glucose. When blood glucose levels are high, the amount of hemoglobin A1c formed in the body will also be relatively higher.
Red blood cells in the human body typically have a lifespan of about 120 days. Before the cells die, the level of hemoglobin A1c in the blood remains relatively stable, unaffected by daily glucose fluctuations, exercise, or diet. It reflects the average blood glucose concentration over the past 6-8 weeks and is independent of factors such as the time of blood draw, whether the patient is fasting, or whether insulin is used. Therefore, it is the best indicator for assessing the effectiveness of blood glucose control in diabetic patients over a certain period.
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