How to reduce the dosage of prednisone when taking 10 doses for nephrotic syndrome?

Patient's question:

Nephrotic Syndrome, Minimal Change Disease in the Glomeruli, started taking 10 tablets of Mezol, took it for half a month, and after a follow-up check, everything has improved. Originally, there were 3+ proteins, now there are none. The doctor said to reduce the dosage, from 10 to 9 tablets, and then reduce one tablet every two weeks. However, this drug has a strong rebound effect. In my case, can I reduce one tablet per week? What problems might arise from reducing one tablet per week? How can I reduce it in the best and safest way?

Doctor's answer:

Hello, from the situation you mentioned, it is not advisable to reduce the dosage too quickly. The method of reduction you mentioned is definitely not feasible; it must be done gradually. Otherwise, the condition is very likely to rebound. As for the side effects of the medication, there is no need to worry too much. They will gradually lessen and disappear after you stop taking the medication.

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