Patient's question:
Hello, doctor! I am an HBV carrier with a small three positive result, and my DHA virus test was negative. During childbirth, my child received an injection of hepatitis B immune globulin (100 units) in the right arm and an injection of hepatitis B vaccine in the buttocks within half an hour after birth. The day after birth, my child received the BCG vaccine in the left arm. Later, because my child had pneumonia and was in recovery, only one additional dose of hepatitis B immune globulin (100 units) was given at the 31st day, but the second dose of hepatitis B vaccine (10 micrograms) was not administered until two and a half months later. Could this affect the effectiveness of mother-to-child transmission prevention?Doctor's answer:
According to your description, your main issue is the use of the hepatitis B vaccine. Advice: Considering your specific situation, first, the use of the hepatitis B vaccine involves receiving one dose of hepatitis B immune globulin and one dose of the vaccine immediately after birth, followed by another dose of the vaccine one month later, and a third dose six months later; alternatively, you can receive one dose of hepatitis B immune globulin at birth, followed by another dose of hepatitis B immune globulin one month later, and simultaneously receive the hepatitis B vaccine. Subsequently, you should receive another dose of the vaccine one month and six months later, respectively. Based on your description, it seems that the vaccine was not administered according to the recommended schedule, which may theoretically affect the production of hepatitis B antibodies. We recommend that you take your child to the hospital for a hepatitis B antibody test to check if antibodies have formed. If not, vaccination should be administered promptly. Additionally, there are no strict requirements for the injection site, so you do not need to be too anxious.