Patient's question:
A skin disease characterized by scaly shedding, typical symptoms include dry skin all over the body with grayish-brown scales and deep, heavy patches. It starts with white scales, resembling "fish-scale" or snake-like skin. It worsens in winter and improves in summer. Generally, there are no conscious symptoms, or only slight itching. If left untreated for a long time or treated improperly, it can affect the entire body and be inherited to the next generation. It appears on the extensor sides of the limbs but not in the armpits or elbow creases in infants.Doctor's answer:
Ichthyosis is hereditary, accounting for 70-80% of cases. The mode of inheritance varies depending on the type. It is primarily classified as dominant, recessive, or co-dominant. Inheritance controlled by a dominant gene is called dominant inheritance, while inheritance controlled by a recessive gene is called recessive inheritance. If the alleles do not exhibit a dominant or recessive relationship, and the characteristics of both alleles of a pair are expressed, it is called co-dominant inheritance. There are still many unclear issues regarding the inheritance of this disease. In addition to genetics, this condition is also related to environmental factors, diet, and disease-induced genetic recombinant variations.