What should be done if a newborn experiences brain hypoxia?

Patient's question:

How is neonatal brain hypoxia caused? How to care for children with this condition?

Doctor's answer:

Hello: Neonatal hypoxic-ischemic encephalopathy is prone to intracranial hemorrhage, and almost all neonates with intraventricular hemorrhage have a history of hypoxia. Therefore, mannitol should be used cautiously or sparingly in neonates to avoid sudden intracranial pressure drops that could exacerbate intracranial hemorrhage, or sudden increases in blood volume that could lead to heart failure. In contrast, the triple therapy of furosemide plus albumin and dexamethasone for neonatal intracranial hypertension is effective, with a slower and more sustained action, without the side effects of mannitol. However, in some critically ill patients, when respiratory failure has already endangered life, a small dose of mannitol (0.25 g/kg) can be administered slowly intravenously on the basis of the above treatment. Dexamethasone should be used in high doses (0.5-1 mg) every 4-6 hours until symptoms improve, after which the dose should be reduced.

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