Patient's question:
Born 8 hours later, hemolytic jaundice was detected. Total bilirubin was 115, admitted to the neonatal department, blue light treatment. On the second day, bilirubin was 141, blood protein was 180, and the physical condition was normal. Is it serious?Doctor's answer:
Hello, the symptoms of ABO hemolysis are relatively mild, while the consequences of Rh hemolysis are more severe. The following manifestations may occur:1. Jaundice in newborns: This is the most common symptom, usually appearing within 24 hours after birth. Rh hemolysis tends to occur earlier, often within 6–12 hours, and rapidly worsens within 48 hours.
2. Anemia: Mild cases may be difficult to detect, but severe cases can lead to heart failure due to anemia. In early ABO hemolysis, hemoglobin levels are rarely below 120 g/L, whereas in Rh hemolysis, levels often drop below 120 g/L within 48 hours after birth. Most Rh hemolysis cases and some ABO hemolysis cases may develop late-stage anemia 3–6 weeks after birth.
3. Hepatosplenomegaly: This occurs during significant hemolysis and is caused by extramedullary hematopoiesis. It is more common in Rh hemolysis.
4. Systemic manifestations: Severe hemolysis may cause lethargy, drowsiness, poor feeding, and reduced crying. In severe cases, death may occur.
It is recommended to conduct maternal blood antibody testing during pregnancy.