Patient's question:
A family with both parents being normal, 8 children, 3 of whom are pituitary dwarfism (2 girls and 1 boy, all over 1 meter tall), and the other 5 are normal. Among the normal children, one girl (150 cm tall) married a man who is 170 cm tall and had a son (170 cm tall) and a daughter (155 cm tall). Will the 155 cm tall girl, when she marries a 170 cm tall boy, have a chance of inheriting dwarfism? If so, what is the probability?Follow-up question: If someone answers without copying the article, please directly answer my question with scientific evidence (I can search online myself; I need a doctor's scientific explanation).
Doctor's answer:
Growth hormone (HGH) is a protein secreted by cells of the anterior pituitary gland and is a peptide hormone. Recombinant DNA technology-produced growth hormone is abbreviated as RHGH. Under normal circumstances, growth hormone (HGH) is secreted in a pulsatile manner. The secretion of growth hormone (HGH) is regulated by growth hormone-releasing hormone (GHRH) produced by the hypothalamus, and is also influenced by gender, age, and circadian rhythms. Secretion significantly increases during sleep.Advice: Sometimes growth hormone can lead to an excessive insulin state, so it is necessary to pay attention to whether the patient exhibits signs of reduced glucose tolerance.