Patient's question:
How long does mifepristone stay in the body before it is metabolized and eliminated? What kind of help do you need: How long does mifepristone stay in the body before it is metabolized and eliminated?Doctor's answer:
This product is rapidly metabolized orally, with the peak time of plasma concentration for mifepristone reaching half-life and full-life being 1.5 hours and 0.81 hours, respectively, and the peak plasma concentrations being 0.8 mg/L and 2.34 mg/L, respectively, but there is a significant individual difference. The elimination from the body is slow, with an elimination half-life of about 20-34 hours. The blood drug level can still be maintained at about 0.2 mg/L after 72 hours of medication. This product has a significant first-pass effect, with the level of metabolites in the blood after oral administration within 1-2 hours already lower than the parent compound.