Patient's question:
Enhancing the K+ concentration in the extracellular fluid of isolated nerve fibers will increase both the absolute value of the resting potential and the amplitude of the action potential. So, what about non-isolated nerve fibers, such as in the human body? What assistance is needed: written plus repetition.Doctor's answer:
The topic you are referring to is physiological techniques. According to the NERSET equation, if the concentration of K+ outside the cell membrane is artificially altered, the measured resting potential value increases when the concentration rises and decreases when the concentration falls. This is primarily determined by the sodium-potassium concentration inside and outside the cell. In the human body, the situation is more complex because the body will spontaneously re-adjust based on the circumstances. For example, if the extracellular potassium concentration rises, the body will quickly pump potassium back into the cells using proton pumps, as high extracellular potassium is very dangerous.