What are the blisters-like things on the hands and feet of a 2-year-old?

Patient's question:

Hand and feet grew things like blisters, just a few days ago. Previous treatment and effectiveness: No treatment has been given yet. What kind of assistance is needed: Wondering what kind of disease it is...

Doctor's answer:

Hand, foot, and mouth disease is an infectious disease caused by enteroviruses, which frequently occurs in children under the age of 5. It can lead to blisters on the hands, feet, and mouth, and in rare cases, complications such as myocarditis, pulmonary edema, and aseptic meningitis and encephalitis. In severe cases, if the condition progresses rapidly, it may lead to life-threatening situations. There are over 20 different types of enteroviruses that can cause hand, foot, and mouth disease, including Coxsackievirus A groups 16, 4, 5, 9, and 10, Coxsackievirus B groups 2 and 5, and enterovirus 71. Among these, Coxsackievirus A16 (CoxA16) and enterovirus 71 (EV71) are the most common pathogens.
Hand, foot, and mouth disease is an infectious disease caused by several types of enteroviruses, primarily affecting children under the age of 5. The disease often manifests as small, grayish-white blisters or red papules, ranging in size from rice grains to green beans, with a red halo around them, appearing on the inner cheeks, tongue, soft palate, hard palate, inner lips, gums, elbows, knees, buttocks, and perineum. The "four" characteristics of the rash are: it does not resemble a mosquito bite, a drug rash, oral or gingival herpes, or chickenpox. When blisters in the mouth break, they form ulcers, often leading to excessive drooling and difficulty eating. Clinically, the rash is not itchy, painful, scabbed, or scarred. Affected children may have yellow urine. Severe cases may also accompany fever, runny nose, and cough. Hand, foot, and mouth disease typically resolves within a week, but if blisters break, it is highly contagious. The disease is characterized by high prevalence, strong transmissibility, and complex transmission routes. The virus can spread through saliva droplets or food contaminated by flies carrying the virus, via the nose and mouth, or through direct contact.
Hand, foot, and mouth disease is an enterovirus infection with an incubation period of 3 to 7 days, with no obvious prodromal symptoms. Most patients develop symptoms suddenly. The disease primarily affects the hands, feet, mouth, and buttocks. Due to the pain from oral ulcers, children may drool and refuse to eat. Oral mucosal rashes appear early, initially as rice-grain-sized macules or vesicles with a red halo, primarily located on the tongue and both cheeks, and also commonly occur on the sides of the lips and gums. Rashes on the hands and feet appear as flat or slightly raised macules or vesicles, which are not itchy. Macules gradually turn darker and fade within about 5 days, while vesicles are round or oval, flattened, and filled with cloudy fluid, aligned with skin creases, varying in size like soybeans. They are generally painless and not itchy, and leave no scars after healing. It is not necessary for all symptoms to appear in the same patient. Blisters and rashes typically resolve within a week.

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