Patient's question:
Seek advice from all the teachers: Our hospital's recommended dose for cefotiam intradermal testing is 0.1ml, with a high positive rate. The package insert suggests using 0.02ml. Clinicians have consulted our pharmacy department, asking whether there is any basis for such a small intradermal test dose. Additionally, such a small test dose makes it difficult to observe carefully. Seeking advice...: What kind of assistance is needed: Practicing many techniques to improve oneself.Doctor's answer:
There are no regulations requiring a skin test, as the value of pre-determining allergic reactions to cephalosporins through a skin test is not significant, as you mentioned, there are many false positives. However, if the instructions for certain cephalosporin products specify "perform a skin test before use," it is essential to use the specific cephalosporin intended for use in the skin test, with a concentration of 300 μg/ml. For cefotiam, you can follow the instructions specified in the drug's manual. If the manual indicates "perform a skin test before use," or if the patient has a history of allergy to penicillin (or cephalosporins), it is absolutely necessary to strictly conduct a skin test.