What is the reason for the 23 alkaline phosphatase test result in a 7-month-old baby with rickets?

Patient's question:

Laboratory test for baby's rickets, alkaline phosphatase, poor sleep at night, bald spot on the head, rib flaring.
History of previous treatment and its effectiveness: The child started taking vitamin D at 40 days of age, 400 units, and at 4 months, the alkaline phosphatase level was 226. The doctor recommended switching to 500 units of Icicle. At 6 months of follow-up, there was no improvement.
What kind of help is needed: What dosage of vitamin D should be taken for treatment, and how long should it be continued?

Doctor's answer:

Rickets, also known as vitamin D deficiency rickets, is a systemic, chronic, nutritional disease characterized by bone inflammation, caused by insufficient vitamin D in infants, children, and adolescents, leading to disorders in calcium and phosphorus metabolism and the development of fibrous incomplete ossification in the growth plate of long bones and bone tissue. Insufficient vitamin D results in fibrous incomplete ossification of mature bone. The above suggestions are for the question "7-month-old baby with rickets and alkaline phosphatase test result of 23," hoping it helps you. Wishing you good health!

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