New Discoveries in the Research of Chinese Medicine Corydalis

Author: Jin Guozhang
Publisher:
Publish Date: 2001-12-01
Features: This book is the first systematic monograph internationally devoted to exploring the relationship between tetrahydroprotoberberine analogs (THPBs) and the effects on dopamine (DA) receptors in the brain, covering various aspects of neuroscience. It begins by discussing the traditional Chinese medicine and pharmacological research on Corydalis, introducing the pharmacological effects of tetrahydropalmatine, such as analgesia, sedation, and anxiolytic effects, along with their mechanisms and clinical applications. Its the research field of THPBs acting on the DA nervous system, discovering that tetrahydropicrotoxinine exhibits a dual effect on DA receptors—D1 agonism and D2 blockade. This is a novel pharmacological action, systematically elaborating on its mechanism and the potential for treating psychiatric disorders. The book delves into many profound and extensive explorations of the pharmacological effects of THPBs.