Patient's question:
How is Nephrotic Syndrome Caused?Doctor's answer:
Friend: Hello! Many diseases can cause damage to the glomerular capillary filtration membrane, leading to nephrotic syndrome. Two-thirds of adults and most children with nephrotic syndrome have primary nephrotic syndrome, including primary glomerulonephritis (acute, chronic, and rapidly progressive types). According to pathological diagnosis, it mainly includes: minimal change disease, membranous glomerulonephritis (membranous nephropathy), mesangial capillary proliferative nephritis (membranoproliferative nephritis), and focal segmental glomerulosclerosis. The causes of secondary nephrotic syndrome include: infections, drugs (mercury, organic gold, penicillamine, and heroin, etc.), toxins and allergies, tumors (lung, stomach, colon, solid breast tumors, and lymphoma, etc.), systemic lupus erythematosus, allergic purpura amyloidosis, and diabetes, among others. One-third of adults and 10% of children with nephrotic syndrome can be caused by secondary factors.