Patient's question:
A family where both parents are normal, 8 children of whom 3 are pituitary dwarfism (2 girls and 1 boy with heights over 1 meter), and the other 5 are normal. Among the normal children, one girl (height 150 cm) married a man (height 170 cm) and had a boy (height 170 cm) and a girl (height 155 cm). Will the 155 cm girl, when she marries a 170 cm boy, have a risk of inheriting dwarfism? If so, what is the probability?First follow-up question: If someone answers without copying the article, please directly answer my question with scientific evidence (I can search online myself; what I need is a doctor's scientific explanation).
Doctor's answer:
Growth hormone (HGH) is a protein secreted by cells of the anterior pituitary gland and is a type of peptide hormone. Growth hormone produced through recombinant DNA technology is abbreviated as RHGH. Under normal circumstances, growth hormone (HGH) is secreted in a pulsatile manner. The secretion of growth hormone (HGH) is regulated by growth hormone-releasing hormone (GHRH) produced by the hypothalamus, and is also influenced by gender, age, and circadian rhythms. Secretion significantly increases during sleep.Advice: Sometimes, growth hormone can lead to an excessive insulin state, so it is necessary to pay attention to whether patients exhibit signs of reduced glucose tolerance.