Patient's question:
My girlfriend's grandmother has a mental illness, but she has borne two daughters without any issues. My girlfriend is perfectly normal, but I'm wondering if our future children will inherit this condition. I hope professionals can help analyze this. Please don't just copy and paste; provide a professional perspective to help me understand the situation. Currently, my mother strongly opposes our relationship, and I'm very upset. I sincerely hope everyone can help me. Thank you!Doctor's answer:
During the pre-marital health check-up, it's recommended to get tested at the hospital. From a biological perspective, this disease is an inherited recessive genetic disorder. Your girlfriend's grandmother has the recessive genetic trait for mental illness, which can be denoted as aa. Her grandfather should then be AA. As a result, their two daughters would be Aa, carrying one recessive gene. Your fiancé could be either AA or Aa, and your girlfriend could be either AA or Aa, since her mother carries one recessive a. If your family has no history of mental illness, the likelihood of you carrying the a gene is low. Therefore, in general, the chances of your child developing the disease are small, primarily depending on whether you carry the a gene. If you are AA, there would be no issues at all.