Sickle cell disease babies need to get vaccinated?

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Doctor's answer:

Hello, Glucose-6-Phosphate Dehydrogenase Deficiency, also known as G6PD deficiency, is commonly referred to as favism, and it is a common congenital genetic disorder. Patients cannot properly metabolize glucose. In addition, foods such as broad beans, camphor, mothballs, gentian violet (purple dye), and certain medications can trigger acute hemolytic reactions in patients. Symptoms include jaundice, poor mental state, and in severe cases, rapid breathing, heart failure, or even shock. Patients must avoid hemolytic reactions caused by food and medication and should also receive antiviral vaccinations (such as the hepatitis A vaccine) to prevent the disease. In cases of severe hemolytic reactions, patients may require blood transfusions, and if kidney failure occurs, they may need hemodialysis. Since the blood transfused to patients does not have G6PD deficiency, blood transfusions are an effective method during an episode. The spleen is the organ responsible for breaking down red blood cells, and spleen removal may help some patients. Any disorder that causes high turnover of red blood cells should be treated with folic acid. Although vitamin E and selenium have antioxidant properties, their use does not reduce the severity of G6PD deficiency.

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