What should I do if the free-hCG result is high in the triple test?

Patient's question:

Early pregnancy results (13 weeks): PAPP-A 6230 mU/L corrected MOM 1.37 free-hCG 81.5 g/mL corrected MOM 1.88 NT 1.2 mm corrected MOM 0.71
Mid-pregnancy results (16 weeks): free-hCG 44.6 g/mL corrected MOM 2.52 hAFP 42.9 U/mL corrected MOM 1.15 uE 34.35 mol/L corrected MOM 0.92
Risk value for Trisomy 21: 1:32000
Risk value for Trisomy 18: 1:100000
NTD low risk.

Doctor's answer:

Analysis of the condition: Hello: If free-β-HCG > 2.5MOM indicates an increased risk of trisomy 21. However, a single test has a relatively high false-positive rate. Generally, Down syndrome screening involves the combined monitoring of multiple indicators. Based on your results, the risk values for trisomy 21 syndrome and trisomy 18 syndrome are both low risk, suggesting that there should be no issues. If there are no children with Down syndrome in your family, further testing is not necessary. If there are, it is best to consider an amniocentesis.
Advice: Hello: If free-β-HCG > 2.5MOM indicates an increased risk of trisomy 21. However, a single test has a relatively high false-positive rate. Generally, Down syndrome screening involves the combined monitoring of multiple indicators. Based on your results, the risk values for trisomy 21 syndrome and trisomy 18 syndrome are both low risk, suggesting that there should be no issues. If there are no children with Down syndrome in your family, further testing is not necessary. If there are, it is best to consider an amniocentesis. Wishing you and your baby good health.

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