What should I do if the screening result for Down syndrome is positive?

Patient's question:

Check results AFP: (OD value) 0.164, (MoM value) 0.61
hCG: (OD value) 0.838, (MoM value) 3.77
Screening results Trisomy 21 risk coefficient: 1/165 (high risk)
Low-risk reference risk coefficient: <1/275
Clinical advice: The screening result is positive, indicating a higher probability of the pregnant woman carrying a child with Down syndrome, placing her in the high-risk group. It is recommended to consult and undergo further diagnosis at the relevant clinic.

Doctor's answer:

Analysis of the condition: Down syndrome screening is a method that involves drawing pregnant women's blood serum to detect the concentration of alpha-fetoprotein and human chorionic gonadotropin in the mother's serum. It also combines the pregnant woman's estimated due date, age, weight, and gestational age at the time of blood collection to calculate the risk coefficient of giving birth to a child with Down syndrome. Children with Down syndrome have severe intellectual disabilities, cannot live independently, and are often accompanied by complex cardiovascular diseases, requiring long-term care from family members. This can impose significant emotional and financial burdens on the family.
Advice: Your Down syndrome screening results indicate a high risk, suggesting a greater likelihood of giving birth to a child with Down syndrome. It is necessary to undergo amniocentesis and fetal chromosome testing to confirm whether the child is indeed affected by Down syndrome.