How to Prevent Rh Hemolytic Disease of the Newborn

Patient's question:

Doctor: Hello! I am AB negative blood type, currently pregnant for the second time, and have no history of blood transfusion. I had an induced abortion two years ago (the surgery was performed at 45 days of pregnancy). Could you please tell me if there is a high risk of hemolysis in my child? Additionally, how can I prevent Rh-negative neonatal hemolysis? Thank you very much. Gender:

Doctor's answer:

It is recommended that your partner check their blood type. If it is Rh positive, due to your history of miscarriage, the first child could also develop neonatal hemolytic disease. If neonatal hemolytic disease occurs, active treatment should be initiated, which may include phototherapy combined with medication during pregnancy. In necessary cases, blood transfusion may be performed to reduce the threat of antibody concentration to the fetus. Once the fetus is mature, induction of labor should be carried out promptly. In recent years, passive immunization theory has been utilized: after an Rh-negative mother gives birth to an Rh-positive first child, anti-D immunoglobulin is administered through intramuscular injection to prevent this disease in subsequent children.

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