Low sperm count, poor quality, and balanced chromosomal translocation: How is it treated?

Patient's question:

Sperm density is less than 210^6/mL, A/B sperm are almost non-existent

Doctor's answer:

Hello!
The male has a balanced translocation. Theoretically, the sperm produced would be 1/18 normal, 1/18 balanced, and the rest would be unbalanced sperm, which could increase the risk of early miscarriage in the female and the risk of congenital defects in the fetus. Although the theoretical probability of bad outcomes is relatively high, due to the large number of sperm released during a single ejaculation by the male and the rigorous internal selection process in the female's body, the natural selection process reduces the actual miscarriage rate.
For your situation, if the male's semen quality is acceptable, the first recommendation is to try pregnancy again after adjusting both partners' conditions and avoiding other factors that may cause early miscarriage or fetal defects. It is recommended to undergo amniocentesis between the 16th and 20th weeks of pregnancy to rule out any adverse conditions in the fetus.

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