Can children still have deformities if they have undergone tests like the four-dimensional prenatal screening and the results are normal?

Patient's question:

Previously, all thorough examinations such as 4D and prenatal screening showed that the child was normal. However, suddenly during the late stage of pregnancy, there was an excessive amount of amniotic fluid. Is there a high possibility of the baby being malformed? Is it necessary to undergo an amniocentesis?

Doctor's answer:

According to your description, the amniotic fluid index is 32 cm, and the amniotic fluid has suddenly increased significantly, highly suggesting fetal malformation. Hydrocephalus, fetal kidney abnormalities, and urinary system malformations may all lead to continuous amniotic fluid accumulation. It is recommended that you undergo an amniocentesis. The triple screen mainly tests for trisomy 21 and neural tube defects, while the 4D ultrasound mainly examines fetal heart and organ development. However, as the fetus grows, there may also be changes in its development. Wishing you the best of luck.

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