Patient's question:
A newborn baby, so the whole family is quite affectionate towards this baby. However, my mother-in-law has noticed that my son's eyes are becoming increasingly yellow, and he is not eating dinner as well as before. Now, his urine is also a bit yellow. During the follow-up visit, the doctor confirmed that he suffered from neonatal prolonged conjugated hyperbilirubinemia. What assistance is needed: What are the causes of the onset of neonatal prolonged conjugated hyperbilirubinemia symptoms?Doctor's answer:
The etiology of infantile cholestasis can primarily be divided into three major categories: hepatocyte damage, intrahepatic bile duct disease, and extrahepatic bile duct disease. 1. Currently, there is no evidence of hepatitis A virus (HAV) transmitted vertically from mother to fetus in infants. 2. Cytomegalovirus (CMV) is the leading cause of cholestasis in China. 3. Toxoplasmosis. 4. Parenteral nutrition. 5. α1-antitrypsin (α1-AT) deficiency. α1-AT is a glycoprotein produced by the liver and has strong protease inhibitory activity.