Patient's question:
Trunk skin tissue, mild keratinization of the epidermis, atrophy of the spinous layer, increased melanin in the basal epidermal cells, flattened papillary layer of the dermis, hyperplasia and thickening of collagen fibers in the dermis, decreased skin appendages, and perivascular lymphocyte infiltration (predominantly lymphocytes of few to moderate amount) around the skin appendages and small blood vesselsDoctor's answer:
The prominent feature is skin hardening, most commonly affecting the skin of the hands and feet, and in severe cases, it can lead to generalized skin stiffness. In addition to the skin, systemic sclerosis can also cause visceral diseases, with the most common clinical manifestations being difficulty swallowing, gastroesophageal reflux, interstitial lung fibrosis, pericardial effusion, and renal insufficiency, among others. There are multiple causes for pediatric rheumatic immune diseases. If a child is diagnosed with pediatric rheumatic immune disease, parents need to cooperate with the doctor in active treatment, cooperate with gastrointestinal decompression, and develop good hygiene habits. The child needs a balanced diet and should avoid stimulating and cold foods.