Does the Down syndrome screening only screen for the highest risk values?

Patient's question:

When doing the Down syndrome screening, is it only necessary to do further tests when the risk value is high? Are moderate and low both safe?

Doctor's answer:

Analysis of the condition: Hello, generally speaking, only high-risk test results require further examination for confirmation. The Down syndrome screening is a method that involves drawing pregnant women's serum to detect the concentration of alpha-fetoprotein and human chorionic gonadotropin in the maternal serum, and then calculating the risk coefficient of giving birth to a child with Down syndrome by combining the pregnant woman's due date, age, weight, and gestational age at the time of blood collection.
Guidance: The purpose of the Down screen test is to determine the risk level of the fetus suffering from Down syndrome through blood tests on the pregnant woman. If the Down screen test results indicate a high risk of the fetus having Down syndrome, further confirmatory tests such as amniocentesis or chorionic villus sampling should be conducted.

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