Patient's question:
Normal reference value results UnitAlpha-fetoprotein (AFP) 25.54 U/ml
AFP (MOM) 0.48 0.41-2.49
Free β-hCG (Fre-βhCG) 0.99 g/ml
Free β-hCG (MOM) 0.09 0.26-2.49
Trisomy 18 risk: 1/670 ≥1/350 is high risk for Down syndrome
Trisomy 18 risk: 1/3300 ≥1/270 is high risk for open neural tube defects
Low risk for open neural tube defects
Low risk for age group risk: 1/1500 ≥1/430 is high risk
Trisomy 13 risk: 1/100
Doctor's answer:
Disease Analysis: The triple screen test is a prenatal screening test for Down syndrome. The purpose is to determine the risk of the fetus having Down syndrome by testing the pregnant woman's blood. If the triple screen test results indicate a high risk of the fetus having Down syndrome, further diagnostic tests such as amniocentesis or chorionic villus sampling should be conducted.Guidance: The triple screen test can detect 60-70% of Down syndrome-affected fetuses. It is important to note that the triple screen test only helps assess the likelihood of the fetus having Down syndrome but cannot definitively confirm whether the fetus actually has the condition. In other words, if the blood test results are elevated, the chances of carrying a Down syndrome baby are higher, but this does not necessarily mean the fetus has a problem. Similarly, older pregnant women (over 35) have a higher chance of carrying a Down syndrome baby, but this does not guarantee their fetus has an issue. On the other hand, even if the test results are normal, it does not guarantee the fetus will not be affected.
Currently, the standard practice is for all young pregnant women to undergo the triple screen test. If the results indicate a high risk, further diagnostic tests such as amniocentesis or chorionic villus sampling are performed to determine whether the fetus's chromosomes are normal and whether it has Down syndrome. You should currently undergo amniocentesis.